Goodbye to the Walker clan.
PHOTOS: Family politics
On Friday, ABC announced it was canceling Brothers and Sisters, No Ordinary Family, Off the Map, V and Mr. Sunshine, EW reports.
PHOTOS: Friends stars, then and now
Mr. Sunshine's cancellation comes at a particularly difficult time for its star Matthew Perry; the actor checked into a rehab facility on Thursday to "focus on [his] sobriety" and quipped: "Please enjoy making fun of me on the world wide web."
PHOTOS: Stars who've battled addiction
Last month, the network announced that two of television's most iconic soap operas -- All My Children and One Life to Live -- would not be returning after this season.
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