Whitney Cummings is on the rise!

One year after the 29-year-old comedienne executive produced, created and starred in her own NBC sitcom, Whitney, Cummings is making the leap to the late-night talk show circuit with the help of pal Chelsea Handler.

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Premiering Nov. 28 on E!, Love You, Mean It, is Cummings' own weekly half-hour chat fest that will feature guests and Cummings' take on the latest in pop culture. Ahead of the show's kickoff, Handler gave her friend -- and frequent Chelsea Lately guest -- a few words of advice.

"I have a new talk show on E! produced by my dear friend Chelsea Handler, and she was kind enough to give me some tips on how to host a talk show. No. 1: Get Oxycontin. Already ahead of you, Chelsea. I can't feel anything from the neck down," Cummings, the co-creator of CBS' Two Broke Girls, jokes in a preview from her series.

VIDEO: Jennifer Aniston mocks Chelsea Handler's hygiene on After Lately

: Jennifer Aniston mocks Chelsea Handler's hygiene on After LatelyRead more: http://www.usmagazine.com/celebrity-news/news/chelsea-handler-im-not-going-to-be-jennifer-anistons-maid-of-honor-20121810#ixzz2CnSdLOO2 Follow us: @usweekly on Twitter | usweekly on Facebook VIDEO: Jennifer Aniston mocks Chelsea Handler's hygiene on After LatelyRead more: http://www.usmagazine.com/celebrity-news/news/chelsea-handler-im-not-going-to-be-jennifer-anistons-maid-of-honor-20121810#ixzz2CnSa8PoG Follow us: @usweekly on Twitter | usweekly on Facebook VIDEO: Jennifer Aniston mocks Chelsea Handler's hygiene on After LatelyRead more: http://www.usmagazine.com/celebrity-news/news/chelsea-handler-im-not-going-to-be-jennifer-anistons-maid-of-honor-20121810#ixzz2CnSa8PoG Follow us: @usweekly on Twitter | usweekly on Facebook

For more of Handler's top tips for Cummings, watch the hilarious clip above now before Love You, Mean It With Whitney Cummings premieres Nov. 28 at 10:30 p.m. (EST) on E!

This article originally appeared on Usmagazine.com: Chelsea Handler Gives Whitney Cummings Talk Show Hosting Advice