George Clooney is about to lend his talents to a hot topic in equal rights history -- the overturn of Proposition 8 -- and right behind him is Brad Pitt!

Set to star together on March 3rd's production of "Milk" screenwriter Dustin Lance Black's play, "8," the real-life BFFs will join a star-studded cast including Modern Family's Jesse Tyler Ferguson and Glee's Jane Lynch in depicting the legal process behind the overturn of Prop 8.

PHOTOS: Celebrity LGBT allies

On February 7, a San Francisco, Calif. federal appeals court declared that the 2008 voter-enacted ban on same-sex marriages in California was unconstitutional.

E! News confirms that Angelina Jolie's beau will play the role of Prop 8 opposer U.S. District Chief Judge Vaughn R. Walker while Clooney will man the role of David Boies, an attorney who sought to overturn the highly publicized ban. Their performance will be broadcast on YouTube March 3.

PHOTOS: Out and proud stars

Clooney's new role couldn't come at a more fitting time.

In a new interview with The Advocate, the 50-year-old actor, who's dating blonde beauty Stacy Keibler, professed that he doesn't mind the long-standing rumors that he's secretly in the closet.

PHOTOS: George Clooney's relationships, past and present

"I think it's funny, but the last thing you'll ever see me do is jump up and down, saying, 'These are lies!' That would be unfair and unkind to my good friends in the gay community," Clooney explained. "I'm not going to let anyone make it seem like being gay is a bad thing. My private life is private, and I'm very happy in it."

"Who does it hurt if someone thinks I'm gay? I'll be long dead and there will still be people who say I was gay. I don't give a sh-t."

Get more Us! Follow us on Twitter, Friend us on Facebook, Subscribe to Us Weekly