The bride, a 23-year-old Argentine TV star, wore a lilac chiffon dress and silver heels, while her Grammy winning groom, 35, donned a gray suit.
The newlyweds posed for a mob of fans after tying the knot at the civil registry downtown. They exchanged a kiss and Lopilato tossed her bouquet of orchids into the crowd, according to reports. See more photos from their wedding!
Throughout the day, Lopilato updated her fans about her wedding via Twitter. Thanking her family and friends she wrote, "How beautiful it all was!"
Buble, who dated Emily Blunt for two years and was once engaged to singer-actress Debbie Timuss, began seeing Lopilato in 2009 after meeting her on a South American tour. He proposed to her in front of her family in Argentina in November, according to reports.