- Photo: Universal/Promotional1 of 15
By Melissa Hunter
Villains: What would a hero be without them? "Despicable Me" showcases the life of a supervillain, and it made us reminisce about the villains we love to hate. While there are too many to count (we've seen lists of 100 villains on other sites), we thought we'd cut out the serial killers (sorry, Freddy), the monsters (no go, Predator), the mean girls (SBI, Regina George) and stick to straight up the maniacal, world-dominating variety. So take a look at the beastliest; the thwart-iest; the foil-iest villains pop culture has ever seen.