The Emmys opened with a skit in which host Jimmy Kimmel ran into the women's bathroom crying over his botched Botox. TV stars like Zooey Deschanel, Christina Hendricks, and a naked Lena Dunham hilariously punched his face back to normal. But before Kimmel was cured, Heidi Klum and Ryan Seacrest, who co-hosted the Emmys in 2008, jokingly offered to host the show in Jimmy's place. It was a tough acting gig for Klum. "I actually had to take acting classes for two months for this role," she said before dropping her first joke of the night to Ryan Seacrest on the red carpet. "Where's your box? When we do things together you have to stand on a box."