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Former vice presidential candidate Sarah Palin doesn't find the humor in "Family Guy," calling the show "cruel and cold hearted," yet she had kinder words for Rush Limbaugh on the same controversial issue.

Of a passing reference to her on "Family Guy" made by a character with down syndrome, Sarah said she took it personally and found it to be offensive. "This world is full of cruel, cold hearted people who would do such a thing," she told Bill O'Reilly on "The O'Reilly Factor" Tuesday night.

Her son Trig also has down syndrome. "Trig is going to have a pretty tough, challenging life ahead of him," she said. "Much more difficult than we ever will, so why make it tougher on the special needs community? That's what I thought when I first heard about this episode."

In conclusion, she asked: "When is enough, enough? When are we going to be willing to say, you know, some things just aren't funny?"

She also recently blasted Rahm Emanuel for using the word "retard" in a closed door meeting with liberal activists -- even calling for him to be fired -- yet did not seem to take offense at fellow conservative personality Rush Limbaugh, who used the same term.

On his program, Rush said: "Our political correct society is acting like some giant insult's taken place by calling a bunch of people who are retards, retards ... I mean these people, these liberal activists are kooks."

Sarah says Rush was "using satire" so he could bring to light what Rahm was calling other people.

"Family Guy" is an animated half-hour comedy on FOX, Sunday nights at 9 p.m.