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John Stamos has no mercy in regards to making fun of his former television nieces, the Olsen twins, and that's why we love him!

The hunky actor (seriously how is that man 52 years old?!) teased the crowd at a press event for "Scream Queens," which he will be joining as a series regular this fall, saying that there was a possibility of his former "Full House" co-stars Mary-Kate and Ashley Olsen would be dropping by FOX's slasher series as guest stars.

The cuddle-loving actor, who will be playing a doctor with a fake hand on the comedic horror series, first said that the 30-year-olds would likely be joining the cast of "Scream Queens" -- but then quickly pointed out to the crowd that he was just joking. Oh the disappointment!

Uncle Jesse joked, "That would be amazing! … I can't even get them on my show."

Umm we love Stamos -- and that he's still sticking it to the twins for not reprising their role on "Fuller House," like the rest of the OG cast. We get that the Olsens are fancy sack-wearing fashionistas, but they will always be the two Michelle Tanners to us kids of the '90s!

Meanwhile, at the "Scream Queens" San Diego Comic-Con panel earlier this month, the show's cast and producers said that the series would be moving from a cursed sorority house to a spine-tingling hospital for the second season.

And for all you ladies out there, Stamos isn't the only handsome new face in need of medical attention -- "Twilight" star Taylor Lautner will also be a series regular starting this fall. Emma Roberts, Lea Michele, Abigail Breslin, Keke Palmer and Jamie Lee Curtis will also be returning to make viewers laugh till they cry out in fear.

In addition to the show's high-profile regulars, Colton Haynes and Cecily Strong will be guest starring in upcoming episodes.

The new season of "Scream Queens" premieres on Tuesday, September 20, on FOX. Netflix has yet to announce a release date for season two of "Fuller House" -- but we'll be sure to let the Olsen Twins know when we find out.