But while in principal she's up for having a whole host of siblings for daughter North West, 14 months, the curvaceous brunette admitted the reality of looking after more than one kid proved more challenging than she'd thought.
"I just went to San Diego to give my pregnant sister a break," she explained to DeGeneres. "I took care of my niece, nephew, and my daughter. To bathe them -- all three -- feed them, get them in their pajamas and down for bed, I was literally crying!" she admitted.
"It was so hard, three kids. I don't know how my mom did it with six," she added.
But while getting hands on with three little children left Kardashian weeping, she admits she's not ready to give up on her dream of a big family just yet.
"I'll go for two, but then again I have so many siblings and I love it, they're my best friends and I would love that for my kids. So I'm going to do two and see how it goes. I don't think [I'd have] six, but maybe three or four - I go back and forth."