By Katherine Tinsley
2:01pm PST, Jan 27, 2025
Ozempic and other GLP-1 medications have become popular weight-loss drugs in Hollywood, but former Biggest Loser trainer Jillian Michaels isn't endorsing using semaglutide to drop some pounds.
According to UCLA Health, semaglutide has a glucagon-like peptide-1 receptor agonist that mimics the GLP-1 hormone in the gut and makes people feel full.
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According to UCLA Health, semaglutide has a glucagon-like peptide-1 receptor agonist that mimics the GLP-1 hormone in the gut and makes people feel full.
MORE: Follow Wonderwall on MSN for more fun celebrity & entertainment photo galleries and content
In an interview, Michaels noted it's expensive to take Ozempic and other alternatives.
"Everything with medication, for me personally, is a cost-benefit analysis," Michaels told Daily Mail.
Semaglutide received FDA approval in 2017 for diabetes, but it has been seen as a miracle solution for rapid fat loss.
"In other words, if you're morbidly obese, if you've tried everything, generally, there will also be a deep psychological component, a physiological addiction, if you have other elements of your health that have failed you, in this cost-benefit analysis, you will absolutely twist my arm," the fitness professional shared.
"If you're taking this to lose 20 pounds, 30 pounds, 45, 50 pounds, I would strongly suggest trying anything else," she added.
"In other words, if you're morbidly obese, if you've tried everything, generally, there will also be a deep psychological component, a physiological addiction, if you have other elements of your health that have failed you, in this cost-benefit analysis, you will absolutely twist my arm," the fitness professional shared.
"If you're taking this to lose 20 pounds, 30 pounds, 45, 50 pounds, I would strongly suggest trying anything else," she added.
One of Michaels' concerns is that patients will struggle to maintain their size once they're no longer using the substance.
"Once they get off of the drug, it does the rebound effect," she told the outlet.
"So you're not gaining anything. You get off the drug in a year and go all the way back. You've not learned anything," she noted. "You've not built any physical strength or endurance. You haven't learned how to eat healthy."