And yet, the 34-year-old actor -- currently engaged to model Audra Marie -- insists he doesn't keep in shape out of vanity. "If Alcide was described as weighing 300 pounds with a comb-over and missing his front teeth, that's what I would look like," the modest actor tells the July issue of GQ.
Still, it can't be easy to disrobe in front of an entire crew of people -- let alone costars Anna Paquin, Stephen Moyer, Alexander Skarsgard and Ryan Kwanten.
"Once they yell action," Manganiello says, "you're a werewolf and you're not thinking about it. But before, there's a boom guy crouched behind you at ass level."