The 56-year-old music icon is showcased once more in the publication -- on newsstands April 14 -- in celebration of their 50-year anniversary. She posed for not one, but four different covers.
While Madonna seems more comfortable in her own skin than ever before -- "You need to know who you are, what you stand for and why you're here," she said -- she thinks the world has a long way before they completely accept her. "Don't be fooled, not much has changed -- certainly not for women. We still live in a very sexist society that wants to limit people," she said when asked about ageism and sexism. "Since I started, I've had people giving me a hard time because they didn't think you could be sexual or have sexuality or sensuality in your work and be intelligent at the same time. For me, the fight has never ended."
As for any of her haters on the web, she has one message for you: "Could you say it to my face? Would you say it to my face? I doubt it."
Madonna recently released her "Rebel Heart" album that features the song "Illuminati," produced by controversial artist Kanye West. She confessed that her and West's opposing visions (and perhaps egos?) did cause arguments. "It's a little bit of a bullfight, but we take turns," Madonna admitted of working with the 37-year-old rapper. "He knows that he's walking into a room with a person with a strong point of view, and I do too. I listen to what he has to say, take it in, and he listens to what I say and takes it in."
She added, "We didn't agree on everything, but he has good ideas."