The rapper, who recently revealed he suffers from epilepsy, was reportedly taken to Cedars-Sinai Medical Center in Los Angeles by his bodyguards.
Wayne responded to the reports on Wednesday, posting on Twitter, " I'm fine. Thank u."
According to TMZ, he was treated by doctors and was discharged early on Wednesday. People reported that reps for the rapper did not return calls seeking comment, but a source told the mag that Wayne is doing "great."
The hip-hop star, whose real name is Dwayne Carter Jr., has been in and out of the hospital in recent months. He collapsed on the set of Nicki Minaj's video shoot for her single "High School" in March and was admitted to the intensive care unit at Cedars-Sinai the next day after suffering three seizures back to back.
It was only then, after being released from medical care, that Wayne, 30, opened up about his health troubles and told fans he has been struggling with epilepsy since he was a child.