Drew made her Hollywood breakthrough as Elliott's 5-year-old kid sister and partner in crime. A scion of the Barrymore acting dynasty, Drew was born to be on camera. Following "E.T.," she continued to land roles in major movies and even scored a Golden Globe nomination at 9 years old for Best Supporting Actress in "Irreconcilable Differences." But early success took its toll on Drew, who began partying, using drugs and drinking before she was a teenager. From posing nude in Playboy to baring her breasts on "Letterman," Drew's rebellious phase played out in the public eye.